Recently, sweat-sensing technology has become a hot segment of smart wearable devices, and the US Air Force and the Rugby League NFL have participated in it. On October 8, sweat sensor developer Eccrine Systems announced a $5.5 million Series A round of financing, of which 4 million came from the US Air Force. On October 18th, another liquid water sensor developed by GraphWear, a smart wearable device company, announced that it has cooperated with the NFL of the American Football League to carry out technical verification and auxiliary research and development.

The sweat sensor will be the vent of the next smart wearable medical device

Science in sweat

Smart wearable devices help us understand and monitor our physical condition by collecting physiological data from the human body. From simple stepping to traditional heart rate, body temperature, and now sweat analysis, smart wearable devices are beginning to track more and more human physiological data. Do not underestimate the sweat. In addition to salt, a drop of sweat contains various scientific codes in our body, including hydration levels, electrolyte balance, lactate index, blood sugar levels, and calorie burning values. Researchers believe that by measuring various electrolytes, metabolites and other components in sweat, combined with the user's body temperature, heart rate and other data, more accurately analyze the user's physiological conditions, determine whether it is in fatigue and dehydration, timely to the user Reminder to prevent excessive exercise.

The sweat sensor will be the vent of the next smart wearable medical device

At present, most of the smart devices for analyzing sweat have not yet been commercialized, and the detection sensitivity, the size of the device, and the combination and practicality of the human body are problems that need to be broken. It is common to use body fluids to detect physical conditions. Most hospital tests rely on various body fluids, but sweat with a lot of life information has not been selected. Major scientific research institutions want to make further breakthroughs in sweat sensing technology to achieve non-invasive testing.

The sweat sensor will be the vent of the next smart wearable medical device

In August of this year, postdoctoral researcher of the University of California, Berkeley, boarded the MIT Science and Technology Review's annual youth hero list with a fully flexible sweat sensor. The Javey Research lab, composed of Gao Wei and instructor Ali Jiewei, saw the possibility of non-invasive testing in the sweat on the future. The chemical composition of sweat is diverse and easy to obtain. In the initial version of the sweat sensor, their design set five detection dimensions: glucose, lactic acid, sodium ion, potassium ion and body surface temperature, and also continuously added heavy metal, chloride ion and other detection objects. These specific test objects can peek into the secrets of the body. Gao Wei said that it is already medically convinced that sodium ions in the blood can detect the dehydration of the body. Chloride ions can be used to diagnose cystic fibrosis. For example, glucose in the human body is related to glucose in the blood. Can be used to detect diabetes.

In addition to the university's scientific research institutions to decode the secrets of sweat, there are also many start-ups that are launching or preparing to launch sweat-related devices and have gained the favor of capital.

Eccrine Systems

The sweat sensor will be the vent of the next smart wearable medical device

Eccrine Systems is a privately held company established in 2013 and headquartered in Cincinnati, Ohio. The company is committed to improving human health, safety and productivity through sweat sensor technology. Its commercial technology and intellectual property are from the University of Cincinnati and are supported by CincyTech. On October 8, the company announced the completion of a $5.5 million Series A financing. Company co-founder and CEO Robert Beech said at a press conference: "Sweat is the best source of non-invasive means of obtaining molecular data and physiology data. In the medical world, these data were previously obtained from the blood. The application of sweat is often limited by the lack of real-time data in the daily life of the human body, including work, sleep, entertainment, etc. Today, microfluidics, nanotechnology, Advances in technologies such as microelectronics and energy management have made it possible to monitor sweat molecules in real time through sensing systems."

The sweat sensor will be the vent of the next smart wearable medical device

The US Air Force is also very interested in the study of sweat, and Eccrine has funded $4 million for a future five-year research program that provides real-time body monitoring and functional enhancement training for ground forces soldiers and pilots. Researchers at the US Air Force want to use a reliable means of studying the molecular level and quantification of the body, but not by blood. Researcher Joshua Hagen said that the laboratory has now tested multiple prototypes in US special forces and is the earliest adopter of the technology.

Of course, sweat can also help researchers study the physiology of pilots. For example, the US Department of Defense collects a large amount of data from billions of dollars of fighters (F-22 and F-35 fighters), but the data is Revealing the physical condition of a pilot who is under high pressure in an aircraft does not provide too much valid information. Determination of a component of the sweat called cortisol is currently a key study of Eccrine, a hormone that acts as a key stress marker in the body. Dehydration status and cortisol testing are the first important tasks for sweat monitors in pilots, and this will be done in the next 2-4 years.

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