Release date: 2016-04-18 Recently, at the 2016 International Liver Disease Conference in Barcelona, ​​Spain, researchers from Italy reported their experimental results using a mouse model, suggesting that adding coffee to the diet of patients with nonalcoholic fatty liver may help Improve the condition. The study found that daily intake of a certain amount of coffee (equivalent to 6 cups of espresso per day for people weighing 70 kg) can improve some of the key markers in the NAFLD mouse model induced by the high-fat diet. These caffeine-intake mice also weighed less than the control group. The scientists also found that coffee helps reduce NAFLD by increasing the expression of a protein called Zonelin-1, which reduces intestinal permeability. Experts believe that increased intestinal permeability will promote liver damage, aggravating NAFLD, patients with NAFLD may develop liver fibrosis, further development may lead to cirrhosis, life-threatening. The study's author, Vincenzo Lembo, said: "Early studies have demonstrated how coffee reverses the damage caused by NAFLD, but this study confirms for the first time that coffee can also affect the permeability of the small intestine. These results also indicate that coffee can reverse NAFLD-related conditions, such as balloons. Degeneration (a form of hepatocyte degeneration)." In their study, the researchers analyzed three groups of mice on a 12-week diet, with the first group taking the standard diet, the second group taking the high-fat diet, and the third group taking the mice. A high-fat diet with low caffeine solution was added. The results showed that adding coffee to a high-fat diet significantly reduced cholesterol, alanine aminotransferase, and liver cell fat content, and improved balloon-like degeneration. At the same time, it can reduce the weight gain of mice over a period of time. The results of the study also showed that ingestion of coffee can cause some changes in the tight junction of the small intestine and reduce the permeability of the intestinal wall. One expert said: "This study reinforces our understanding of the association between coffee and nonalcoholic fatty liver. Although it is not clear whether the intake of more coffee is beneficial to the improvement of human nonalcoholic fatty liver disease, But it still provides important insights into the role of coffee in combating NAFLD." Source: Bio Valley Fingerprint Lock Safe Box,Fingerprint Lock Safe,Fingerprint Lock Box,Fingerprint Safe Hebei Tiger Brand Group Jia Bao Cabinet Industry Co. LTD , https://www.cntigersafe.com