Suzhou Medical Institute developed an objective detector for digital optic nerve function

Suzhou Medical Institute developed an objective detector for digital optic nerve function

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Recently, the Medical Machine Vision Laboratory of the Medical Imaging Room of the Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, under the leadership of the project leader Fu Weiwei, developed a digital quantitative RAPD (relative pupillary afferent disorder) for the diagnosis of optic nerve diseases. instrument. The detector can independently and quantitatively detect the whole process of light reflection of the pupils of the eyes, and can be used for clinical quantitative diagnosis, therapeutic evaluation and prognosis evaluation of optic nerve pathway and other diseases related to optic nerve pathway. Its core technology is internationally leading, and the domestic market is in a blank state, and the potential market space for products is huge.

The pupil-to-light reflection is an autonomic nervous stress response caused by light stimulation that causes the pupil to shrink. This process is accomplished by the pupil to the light-reflecting neural pathway. Pupils are important signs of many diseases, including stroke, optic nerve and retinal diseases, which are often missed for mild symptoms, leading to missed optimal treatment.

Relative afferent pupillary defect (RAPD) is a pupillary afferent disorder caused by the asymmetry of the light intensity of both eyes. RAPD examination is a routine examination method and important diagnostic basis for optic nerve related diseases such as optic neuritis. At present, the clinical use of doctors to manually check the qualitative assessment method, the doctor's individual operation requirements are high, subjective factors have a large impact, and can only give a positive diagnosis for patients with obvious symptoms, can not be detected for mild RAPD.

The digital RAPD detector developed by the research group adopts digital pupil imaging and independent optical path monocular stimulation technology to independently stimulate the left and right eyes respectively, and simultaneously perform high-speed and high-precision synchronous tracking detection on the changes of the pupils of both eyes, and in the form of a curve. Completely shows the entire process of pupil reflection on light. The inspection completely excludes subjective factors, is simple and fast, and the results are accurate. The detection data of RAPD can be quantitatively given and a test report can be issued. The instrument's pupil diameter detection accuracy is sub-millimeter, and the pupil tracking frequency is several hundred hertz, far exceeding the accuracy that can be achieved by manual inspection. For early, mild RAPD, accurate detection can be performed as well. Therefore, it can also be used for the early diagnosis of related diseases, the tracking of treatment processes and the quantitative evaluation of prognosis effects.

At present, the instrument has completed technology development, and the key technical indicators far exceed the similar foreign products, reaching the international advanced level. The project team will actively promote its early industrial transformation and put it into clinical use, in order to improve the backward RAPD inspection method, provide an accurate, fast and convenient new digital RAPD detection instrument for ophthalmology and neurologists, and provide diagnosis and treatment for related diseases. More powerful tools and guarantees.

The main research direction of the Medical Machine Vision Laboratory of the Medical Imaging Room of Suzhou Medical Institute is the development of photoelectric medical instruments, testing instruments and key components. The main work is to use the photoelectric imaging technology, automatic control technology, machine vision technology, image processing technology and low-power embedded system technology to develop and industrialize innovative medical device products. The team has undertaken a number of research projects and corporate commissions, all of which meet the standards and are delivered to Party A. They have rich experience in the development of optical and electrical medical products . At present, it is working with a number of organizations to develop ophthalmic imaging diagnostics, therapeutic instruments, and cell counting and imaging detection instruments based on optical imaging, automatic control and image processing technologies.

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