Release date: 2016-06-27 It is well known that human genetic material has mitochondrial DNA in addition to DNA (deoxyribonucleic acid) in the nucleus. An international team said on the 24th that they have discovered why mitochondrial DNA cannot pass through the father's sperm, but can only be passed on to the offspring through the mother's egg. Mitochondria are organelles that provide energy in cells and are called "energy factories" of cells. The study, published in the new issue of the journal Science, states that when sperm and eggs are combined into fertilized eggs, the mitochondria in the sperm initiate a self-destructive mechanism. If the mechanism is delayed, the embryos that develop from the fertilized eggs are less likely to survive. Professor Xue Ding of the University of Colorado at Boulder, who is in charge of research, explained to Xinhua News Agency that the mitochondria of the father existed in the sperm, and the sperm needed mitochondria to generate a lot of energy to compete with other sperm in the swimming. Under heavy load, the mitochondria produce a lot of oxygen free radicals, which can induce mutations in mitochondrial DNA, so nature has evolved a mechanism to remove mitochondria from the father from the fertilized eggs. Schröding et al. found that an enzyme called CPS-6 plays an important role in the removal of the mitochondria of the male parent, and studies the sperm mitochondria of C. elegans. The results show that after the sperm and the egg are combined, the enzyme is from the parent. The mitochondrial membrane mesenchyme is translocated into the mitochondrial matrix, which is the site of mitochondrial DNA, which degrades and clears mitochondrial DNA. If the researchers take interventions to allow the paternal mitochondria to degrade in the late stages of development, the likelihood of embryonic death increases, indicating that the inheritance of the mitochondria is unfavorable for evolution. The researchers say that mitochondrial maternal inheritance is "a fundamental and important biological problem," and their research provides an explanation for this phenomenon. Source: Xinhua News Agency Electro Hydraulic Operating Table General Surgical Table,Orthopedic Surgery Table,Electro Hydraulic Operating Table,Electro Hydraulic Surgical Table NINGBO MEDICAL EQUIPMENT CO.,LTD , https://www.techartmeds.com