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Broad-spectrum penicillins, in addition to amoxicillin, and ampicillin, apply to respiratory tract, urinary tract, gastrointestinal tract, and skin and soft tissue infections caused by sensitive bacteria. However, it may also cause allergic reactions when used, common with rashes, itching, fever, asthma, and hematuria. Some people have symptoms of pruritus, rash, dizziness, and numbness of the limbs after taking hot water or taking amoxicillin capsules and granules, which is probably caused by too high water temperature.
Decomposition products of penicillin drugs and proteins combine to form antigens and cause allergic reactions. The macromolecule polymer that causes an allergic reaction increases with time and temperature, so flushing the amoxycillin particles with hot water will accelerate the production of polymers and increase the allergic reaction.
The allergic symptoms of amoxicillin mainly include dermatological reactions (about 46%), anaphylactic shock (22%) and renal impairment (6.3%), and tinnitus, lymphadenopathy, syncope and other symptoms may occur in a minority. It is best to blunt or send pills containing penicillin with warm boiled water no higher than 40°C, or cold boiled water, and the capsules are also delivered with water at the same temperature.
Improper storage of penicillin antibiotics may also produce high molecular impurities and should be kept sealed; do not put the pill box on the window or in the car, avoid heating or stoves to avoid heat deterioration. Amoxicillin is a prescription drug and should be used under the guidance of a doctor. Those who are allergic to penicillin should not use it without authorization. Pregnant and lactating women should be used with caution. For safety reasons, it is best to take the first dose in the hospital and leave after 30 minutes.