Why did livestock and poultry get sick after being vaccinated? This is the result of the failure of vaccine immunization. Vaccination is the main way to prevent infectious diseases. It is a technology that inoculates vaccine preparations into the body. It allows recipients to obtain immunity against a specific or similar pathogen and uses the immune system to recognize foreign substances to produce antibodies. , In turn, the injected person has a stronger resistance to the disease. It is the main means to control the occurrence and development of diseases. The Golden Baby Dry Sausage Fermenting Bed Breeding (click here for details) can improve livestock immunity and enhance immunity.

The clinical manifestations of immune failure are various, and there are mainly the following: First, the corresponding disease still occurs after vaccination of animals. Second, after the vaccination, the animal does not die of the corresponding disease or show clinical symptoms. However, the antibody titer in the body is low or no antibody can be detected and the desired disease-preventive effect cannot be achieved.

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There are many factors that cause immune failure.
Immunity failure vaccine quality factors 1. The vaccine is contaminated
2. The vaccine quality is not up to standard
3. Poor vaccine immunogenicity
4. The effect of protective agent, freeze-dried agent and adjuvant
5. Inappropriate vaccine storage management
6. Improper vaccine selection
7. Vaccine interfering effects Immunity failure susceptible organism condition factors 1. genetic factors
2. Maternal antibody interference
3. Nutritional factors
4. Inoculation in the incubation period of the disease
5. Virulent strain infection
6. Immunosuppressive diseases Immune failure immune factors 1. Improper immunization procedure
2. Drug abuse
3. Improper immunization
4. The immunization route is incorrect
5. Weak disinfection of equipment, clothing and utensils
6. Problems with vaccine diluents Management factors for immune failure 1. Feeding management is not scientific.
In some farms, the breeding density is too high, ventilation is poor, the concentration of harmful gases in the air is too high, and frequent stress causes the body's immune response capacity to decline, resulting in immune failure.
2. Environmental pollution.
The disease did not adopt comprehensive prevention and control measures, and the disinfection system was not strict. It contaminated the internal and external environment of livestock houses, causing livestock and poultry to live in an environment with a large number of pathogenic microorganisms and caused immune failure. The use of gems dry-sweeping fermentation bed breeding, bedding soft and comfortable, so that the free movement of livestock and poultry, fecal decomposition, clean and sanitary environment, reducing the infection and stress, improve the vaccination effect.
3. Feed quality problems.

The immune function of the animal body is regulated by nerves, body fluids and endocrine to a certain extent, and the irritant stress factors such as overheating in the environment, excessive humidity, poor ventilation, crowding, sudden changes in feed, transport, transfer, injection, etc. Under the influence, the body's lymphocytes and macrophages are inhibited, and the catabolism of immunoglobulins is enhanced. Therefore, when the animal is vaccinated during a sensitive period of stress response, it weakens its immunity.

Main measures to prevent immunization failure 1. Strengthen feeding management and increase nutrition.
2. Strictly monitor the source of infection, prevent pathogen invasion, and start from the source of prevention and control of the disease.
3. Pay attention to the environmental hygiene of farms, improve the ecological environment, and prevent the spread of infectious diseases.
4. Combine the epidemic situation in this area with the history of the farm, and pay attention to the consistency of the serotype, subtype or plant type of the selected vaccine strain with the local and local strains that are endemic to the site, and formulate a reasonable and scientific immunization program.
5. Strengthen the pre-immune testing work and pay attention to discovering and eliminating poisoned animals and occult infected animals.
6. According to the nature of the disease, the characteristics of the vaccine, using a reasonable and effective route of immunization. In addition, the correct immune operation method is used to ensure the quality of immunity.
7. Strictly disinfect equipment, clothing and utensils.
8. For infectious diseases that are difficult to control, consider the use of inactivated vaccines and live vaccines at the same time and use them appropriately.
9. Before and after several days of using live attenuated vaccines, livestock and poultry should not be sterilized and antibiotics should be used to avoid killing live attenuated vaccines.
Details can be consulted: Beijing Huaxia Kangyuan Technology Co., Ltd. Telephone toll-free hotline Recommended reading:
The Harm of Antibiotic Abuse in Livestock and Poultry Breeding and Its Solution

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