Pharmacological effects

Xinjiang blue thorn head:

1 Effect on the central nervous system

The effect of the blue echinocandine is similar to that of strychnine. A small dose has an excitatory effect on animals, a large dose causes spasm, and afterwards, systemic inhibition occurs. It has a wakeful effect on the sleep induced by barbiturates and can stimulate neuromuscular devices. , to promote the recovery of peripheral nerves

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process. Clinically, it is possible to treat various types of incomplete paralysis and because of peripheral or central motor neurotransmission disturbances, it has a strong effect on patients with systemic weakness based on vascular malnutrition. (It also has therapeutic effects on experimental traumatic paralysis.)

2 Effects on the cardiovascular system

Blue gacilline can cause blood pressure drop and increase cardiac contractility in anesthetized cats. Heart systolic tension can be increased and systolic amplitude can be decreased in isolated frog hearts. High concentration can stop the heart in systole and show blood vessels in isolated rabbit ears. expansion. The fruit is used in patients with hypertension and atherosclerosis abroad as a cardiac agent.

3 other

Blue gacilline can increase the cat's intestine tension in vitro and inhibit the rabbit's isolated gut. The detrimental effect is more severe than that of the gentry. The dose (3 to 6 mg/kg) for raising reflex activity is very different from the lethal dose (600 to 650 mg/kg), and the toxicity is low.

Pharmacological effects:

1. Effects on the Central Nervous System Lanciniamine is similar to strychnine in that it exhibits a stimulant effect on animals at low doses, a large dose causes paralysis, and systemic suppression occurs thereafter; it has a wakeful effect on sleep induced by barbiturates. And can stimulate the neuromuscular device to promote the recovery process of peripheral nerves. Clinically, it can treat all kinds of incomplete paralysis and the palsy of peripheral or motor neurotransmission disorders. It has a strong effect on patients with systemic weakness based on vascular malnutrition. There is also a therapeutic effect on experimental traumatic paralysis.

2. High concentrations of the cardiovascular system can stop the heart from contracting. Perform vasodilation on isolated rabbit ears.

3. Effects on intestinal smooth muscle Blue gacilline can increase cat intestine tension in vitro and inhibit isolated rabbit intestine. Its role is more weaker than that of the scholars.

4. The anti-fungal effect of Leliu (unknown species) flooding agent (1:3) has different degrees of inhibitory effect on dermatophytes such as Xanthococcus xanthus and Nocardia star in vitro.


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