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Autumn is a good time for livestock and poultry to focus on deworming. To completely repel insects and prevent drug poisoning, the following points should be mastered. First, rational selection of drugs, pay attention to match. It is necessary to select broad-spectrum anthelmintic drugs with a wide range of insect repellent, high curative effect, and low toxicity based on livestock and poultry species, age, species of infected parasites, parasitic sites, etc., taking into account expenditures. Since parasitic diseases are mostly mixed infections, appropriate combinations of various insect repellents or direct use of multifunctional broad-spectrum anthelmintics can be used. Such as avermectin (worm insect star) and so on. Second, master the dose, interval medication. All kinds of anthelmintic drugs have certain toxic and side effects on the livestock and poultry. When the insects are dewormed, their doses must be accurate and the poisoning caused by overdose should be strictly prevented. In order to prevent parasites from developing drug resistance, the second dose may be given after the first dose. Third, the method is correct, the way to the right. When a large number of livestock and poultry deworming treatment, or use of a variety of drugs to drive off mixed infection or use of new anthelmintic drugs, should first do a small number of livestock and poultry pre-test to observe the drug response and insect repellent effect to ensure safe and effective before the full promotion. Different drugs or different insect repellent purposes, their medication route is not the same. General ectoparasites are suitable for spraying and medicinal baths (must be performed simultaneously with sheds); blood parasites are good for intravenous injection; respiratory and urinary tract parasites are suitable for oral and intramuscular injection; gastrointestinal parasites are fed early in the morning Fasting before feeding is best. Fourth, breeding livestock and poultry, medication caution. Investigators need to avoid using drugs that have an adverse effect on egg production and fertility. Maternal livestock should not use toxic anthelmintic drugs during pregnancy. The deworming of dairy cows should use an anthelmintic which has no adverse effect on the yield and quality (especially flavor) of fresh milk. De-worming of birds should be carried out before opening, and deworming of breeding stocks must be carried out in the empty period.