Although plants lack many mechanisms for regulating intracellular calcium concentration in mammals, they still use calcium ion signals to help complete a variety of physiological functions. There are still many Ca 2+ regulatory mechanisms that cannot be accurately explained. On May 4, 2018, a University of Maryland scholar published an article on Science entitled "CORNICHON sorting and regulation of GLR channels underlie pollen tube Ca 2+ homeostasis", focusing on the regulation mechanism of Ca 2+ homeostasis in pollen tubes. . In the study, Non-invasive Micro-test Technology (NMT) was used to detect the Ca 2+ uptake rate of the Arabidopsis pollen tube at the wild type (Col-0) and different mutants. Pollen tube tip Ca 2+ flow detection map The results show that the arrangement and activation of glutamate receptor channels (GLRs) are associated with CNIH protein. Pollen tube expression of single mutant Arabidopsis thaliana GLRs (AtGLRs) showed growth and Ca 2+ flow rate indicated by the plasma membrane Ca 2+ channel; however, the high-order mutant AtGLR3.3 showed opposite phenomena to the hypothesis: these Differences can be explained by subcellular AtGLR localization, and the researchers also explored the significance of AtCNIHs in such sorting. They found that the interaction between AtGLRs and AtCNIH pairs produced specific intracellular localization points. AtCNIHs further triggers AtGLR activity in mammalian cells without ligand. Together, these data reveal a mechanism by which AtCNIHs trigger changes in the arrangement and activity of AtGLRs, thereby regulating Ca 2+ homeostasis. Detection of Ca 2+ flow rate in wild type and different types of mutants. Positive value indicates absorption NMT pollen tube research case (1) NO regulates intracellular and extracellular Ca2+ changes and cell wall structure during pollen tube growth (2) Science outlook: ion current and pollen tube tip growth (3) Tobacco pollen tube as a model for ion dynamics research (4) Pollen tube is a model material for studying the anion transport of plant cells (5) Inositol and Cl-flow regulate pollen tube growth and cell volume (6) Mechanism of boron affecting pollen tube growth (7) The role of ion current in the growth of pollen tubes Large to plant tissue, small to single cells, non-invasive with its wide range of measurable sample sizes, its applicable fields cover medical physiology, plant science, animal science, microbiology, environmental science and so on. 1, antibacterial properties Although the size of the bacteria is too small to detect a single individual, methods such as enrichment can be provided to detect the signal of the bacterial layer (below). The non-injury micro-test system directly reflects the physiological state of bacteria by detecting bacterial metabolism, calcium signal and other information, and evaluates the antibacterial properties of various materials. Ion dynamic balance of bacteria "Science" in the United States to restart the bacteriophage antibacterial clinical trial - how to avoid entering the wolves? 2, biodegradability How to improve the biodegradability of materials? Biodegradability is closely related to the physiological state of microorganisms during degradation. Using the non-invasive micro-test system, you can quickly and accurately understand the physiological state of the bacteria, so as to know which chemical and physical properties of the material, in order to have better biodegradability. 3, bionic intelligent interface material The uniqueness of the non-invasive micro-testing system is not only because of its wide range of object sizes, but also materials such as metals and coatings that are not biologically active. As long as there are ions and molecules flowing (diffusion), whether the signal is derived from biological/non-biological samples, non-damage micro-test systems can be detected. At present, it has been applied in the fields of alloys, coatings and biomimetic materials, and has published relevant results. NMT escorts aviation magnesium alloy performance effervescent tablets,vitamin c effervescent tablets,Dietary Supplement ,Nutritional Supplements FOSHAN PHARMA CO., LTD. , https://www.foshanpharma.com