New findings in embryo research or "changing textbooks" July 16, 2018 Source: Xinhua News Agency Author: Zhou Zhou According to Xinhua News Agency, Washington, July 12, scientists believe that during the first cell division of mammalian embryos, only one spindle is responsible for distributing embryonic chromosomes into two cells. But European researchers used the latest experimental observations in mice to find that there are actually two spindles in the process, responsible for the chromosomes from the father and mother. Researchers at the European Molecular Biology Laboratory said in a new issue of the journal Science on the 12th that the latest findings mean that the genetic information of parents is preserved during the first cell division of the embryo. The researchers emphasize that this is the result of a "change textbook" study, which is expected to explain why the first few cell divisions in the early stages of mammalian development are prone to errors, and may even change the definition of life start time in some countries. Jan Allenberg, head of research and the European Molecular Biology Laboratory, said in a statement that we know that simple organisms such as insects have a double-spindle, but the same is true of mammals like mice. "It's amazing." The spindle is a special organelle shaped like a spindle. During the mitosis of animal cells, chromosomes are arranged in the center of the spindle by centromeres. In the latest experiments, the researchers used the light-slide illumination microscopy technology developed by Alan Berg et al. to observe the early development of the embryo in real time, and first observed the existence of two spindles during the first cell division of the embryo. The researchers say that mammalian embryos often have errors in the first cell division process, producing abnormal cells with multiple nuclei, leading to the termination of embryonic development. The discovery of the twin spindle provides a new explanation for this problem and is expected to be used to find new molecular targets. If the final findings are also applicable to humans, then it is expected to provide new ideas for the treatment of infertility. Researchers believe that this discovery may change the definition of life start time in some countries. In some countries, the law states that life begins with the fusion of the nucleus of both sperm and egg after fertilization. But if the discovery of the twin spindle is applicable to humans, then the beginning of life may have to be pushed back slightly, at least after the first cell division. We're professional Gynecology Hysteroscopy
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