Google co-founder Sergey Brin often practice diving. “The diving sport is short and intense,†he said. “You can increase your heart rate immediately.†But diving has another advantage for him. From the perspective of family genetics, Brin is at high risk for Parkinson's disease, and the risk is reduced a little with each hop. In each cell of Brin's body, there is a genetic mutation in the LRRK2 gene of chromosome 12, which is closely related to the incidence of Parkinson's disease. Not everyone with this genetic mutation will develop Parkinson's disease, but it does increase the chance of getting sick. Ordinary Americans have a risk of developing this disease of about 1%, but those with this genetic mutation have a prevalence of 30%-75%. From the DNA of Brin himself, the probability of his illness is 50%. So he took some maintenance measures, exercise, drink coffee, drink green tea... Use environmental factors to offset the effects of DNA. He said, "Diet and exercise can reduce my risk by half to 25%." He believes that the steady development of neuroscience will reduce this risk by half and reduce the possibility to 13 %about. Although these are speculations, his explanations are well-founded and convincing. Of course, Brin is by no means an ordinary person. He has a billion-dollar net worth, which provides him with additional benefits. Since knowing that he has carried a mutation in the LRRK2 gene, Brin has donated at least $50 million to Parkinson's disease research activities, and he believes that the money can "really change the situation." With the increase in research activities, Brin once again adjusted his overall risk of illness, “the risk dropped below 10%.†This is still 10 times the level of the average American, but has a 50% lower risk than his own. A lot. Google style science This sounds so pragmatic and so obvious that it almost made everyone overlook the astonishing fact that many philanthropists have funded research on certain diseases and they have been diagnosed with these diseases themselves. However, Brin may be the first person to donate research funding based on genetic testing, hoping to avoid a disease. Brin’s approach is worth noting that there is another reason. This is not only a public welfare research venture, but Brin is seeking a completely different science. Most Parkinson's disease research work, like general medical research, relies on traditional scientific methods: hypothesis, analysis, peer review, and publication of papers. But Brin proposed a different approach, using computational power and massive data sets to drive research. This method comes from his understanding of the algorithm, with Google's confidence in computing power, the purpose is to speed up the pace of scientific research and enhance the potential of scientific research. "I'm used to the Internet world. In my opinion, the pace of research in the medical world is as slow as the movement of glaciers," Brin said. “We can find a lot of things and collect a lot of information. If we can find a pattern, we can find a way out.†In other words, Brin hopes to find another way to circumvent the centuries-old scientific epistemology and turn to a more Google-style science. He wants to collect data first, then assume, and then discover valuable patterns. And he also has enough money and algorithmic weapons to do this. Family inheritance Brin’s confidence in numbers and his confidence in “knowledge is power†comes from family inheritance. His parents are Russian scientists. When Brin’s mother had some symptoms in 1996, she thought that her aunt had a history of Parkinson’s disease. But at the time the scientific community thought that Parkinson's was not inherited, so Brin did not understand the mother's concerns. "I think she thinks too much, too irrational," he said. However, after further testing, Brin’s mother was diagnosed with Parkinson's disease in 1999. The relationship between LRRK2 gene mutation and Parkinson's disease was discovered in 2004. In 2006, Brin’s wife, Anne Wojcicki, founded the personal gene company 23andMe (Google is one of the investors). As an alpha tester, Brin saw his own genome results very early. Soon after 23andMe found that both Brin and his mother had mutations in the LRRK2 gene. Brin was not alarmed. He spent several months thinking about it and asking an expert. But very quickly, it was unrealistic for him to be aware of the confidentiality of this matter. Brin said, "I am not as open as this. This information seems to be worth sharing. It may even be interesting." So on the day of September 2008, Brin opened a blog. The first article is called "LRRK2" directly. Toxic knowledge? In a sense, we have been using genetics to predict our own risk of disease. When we talk about family history, we are mainly talking about DNA, which is a clue to the health of our parents for our own health. Genetic scanning is nothing more than a more modern way to connect our family history with our future possibilities. But DNA testing is so precise that it may make people think that chemicals determine their fate and feel that it contains dark, ruthless secrets. This is why genetic information is sometimes referred to as "toxic knowledge." In the words of Hank Greely, a bioethicist at Stanford University, giving people direct access to their genetic information is a complete “reckless moveâ€. In the early days of scientific development, this was a bit true. Surprisingly, the notion that genetic information is “toxic†has continued to this day, probably because it assumes that people lack the self-understanding. But research shows that this assumption is unfounded. A study on Alzheimer's disease says that when people are told bad news about the high risk of illness, "expected people will react catastrophically. Depression, suicide, quit work, abandon the family. Research I thought of the worst." But the truth is the opposite. Those who are told to have a higher risk of Alzheimer's disease seem to be able to deal with it with positive energy, and in later life they tend to choose a healthier lifestyle. “People will go to the problem and it doesn’t seem to have any obvious depressive symptoms.†Disposable Paper Tube,Custom Disposable Paper Tube,Medical Paper Tube,Disposable Medical Paper Tube Hengshui Qifei Paper Products Co. LTD , https://www.hengshuiqifei.com