Will the vagina be allergic?

The characteristics of human vaginal mucosal blood flow may affect the concentration of various substances in the vagina, making these substances local or systemic allergens. Semen components, drugs and foods taken by semen neutral partners, spermicides, soaps, sanitary napkins, latex, intestinal parasites, and Candida albicans may trigger immediate allergic reactions, in addition to pollen, dust, or food. The particles may not be brought into the vagina by hand, and may even be absorbed by the whole body. Many studies have shown that the vaginal immune response causes recurrent vaginitis in some patients. IgE antibodies against Candida albicans, semen components, pollen and contraceptive spermicides are found in the vaginal fluid and, in most cases, eosinophils are visible in vaginal smears.

The sensitized original selectively accumulates in the vaginal mucosal cavity and delivers antigen through the ductal system between the mucosal epithelium. It is brought into contact with the mast cells of the lamina propria, and the two react with each other, and the mast cells degranulate and release histamine and other inflammatory mediators, resulting in the manifestation of allergic vaginitis.

Histamine is a macrophage prostaglandin potential inducer that induces the production of prostaglandin E2, and prostaglandin E2 inhibits the cellular immune response. The mechanism against fungi is dependent on cellular immunity, so the resulting Candida vaginitis secondary to primary allergic vaginitis.

How to self-discover allergic vaginitis?

1. The main symptom is the increase of vaginal secretions, which is pus bloody leucorrhea, and there is rot tissue, and there is odor.

2. vaginal examination shows that the formation of vaginal mucosa erosion and ulcers, long duration of the disease, the vagina can form a wide and hard scar adhesions, so that the vaginal stenosis, and even atresia.

3. If the vagina, uterine bleeding, empyema, anal examination can touch the inflated vagina and swollen uterus.

4. There is a clear correlation between the occurrence of symptoms and systemic or topical medication.

Anti-Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a chronic, etiology of inflammatory synovitis-based systemic disease. It is characterized by hand, small joints of the joints, symmetry, invasive joint inflammation, often associated with external organ involvement and serum rheumatoid factor positive, can lead to joint deformity and loss of function. According to statistics, the incidence of rheumatoid arthritis in women is 2 to 3 times that of men.It can occur at any age, high incidence of age 40 to 60 years old. People who has rheumatoid arthritis in the late, severe or long-term bedridden patients, due to combined infection, gastrointestinal bleeding, heart, lung or kidney disease can be crisis to life. The main purpose of treatment for Rheumatoid arthritis is to reduce the inflammation of the joints, inhibit the development of lesions and irreversible bone destruction, as far as possible to protect the function of joints and muscles, and ultimately achieve complete disease remission or low disease activity target. Treatment principles include 1. Patient education, 2. General treatment 3. Drug treatment 4. Immune purification 5. Functional exercise 6. Surgical treatment. Anti-Rheumatoid arthritis drug treatment mainly includes non-steroidal anti-inflammatory drugs, slow-acting anti-rheumatic drugs, immunosuppressive agents, immune and biological agents and botanicals. Over the past decade, the treatment of extra-articular lesions and the emergence of new therapies, so that the efficacy of rheumatoid arthritis has been significantly improved. Most patients with rheumatoid arthritis can get a good control or even complete remission.

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