At the beginning of this year, a 36-year-old former NASA researcher became the world's first officially publicized genetically modified person. He claimed to have transformed his DNA and given himself a powerful arm through his own gene therapy. Not only that, he also sold gene editing tools and released a free set of instructions to guide people on how to use his entry-level tools to carry out their own genetic modification.

The group represented by him is called “bio-hacker”. They invent methods and create attacks, thus reducing the threshold for genetic modification of themselves using enzymes, plasmids, viruses and other media.

At the end of April, a red hacker in the bio-hacking world died in Washington, DC, and he was suspected to have died because he had injected a herpes treatment gene without FDA clinical testing at a bio-hacking conference held in February this year. Pharmacy.

Known as "genetic scissors", the CRISPR/Cas9 technology, because of its use of "stupid", has become a popular tool for editing specific genes at will. Science enthusiasts are free to learn and use, and can edit genes at home, thus becoming the treasure of biological hackers.

In general, bio-hackers choose to try their own medicines or test them on the edge of the law, for example, selling genetic material like muscle growth, and deliberately labeling non-injectable warnings. As for how to use the materials, it is the buyer's own business.

Random editing of the gene is likely to bring about a huge public crisis. It has been reported that the extinct horsepox virus has even been re-synthesized.

Expert Reviews

Unauthorized amateur biologists may release new pathogens or cause other uncontrollable risks. Most of this group is outside the scope of supervision, and their moral constraints are not strong enough, so the risk of such research may be much higher than formal research.

——Han Chunbo, Researcher, Institute of Microbiology, Chinese Academy of Sciences

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