Together with the research team, he discovered a new treatment for "starved" cancer cells, and published it in the international biomedical and medical field elife, which has been recognized by internationally renowned oncologists.

"Cell cancer cells also need to 'eat' things to survive, deprive it of food, cancer cells will die." Hu Yu, a professor at the Institute of Cancer Research at Zhejiang University, said that following this seemingly simple principle, he and the research team discovered The new treatment of "starved" cancer cells, published in the international biomedical field authoritative magazine elife, has been recognized by internationally renowned oncologists.

After many years of basic research, Hu Wei discovered that glucose is a thing that cancer cells must “eat”. It is reasonable to see that deprivation of glucose cancer cells will die. But in fact, when the supply of glucose is insufficient, the tumor does not starve and grows.

Professor Hu Wei said the mystery: there is a large amount of lactic acid in the tumor, and the lactic acid dissociates into lactate anion and hydrogen ions, which become the two "helpers" of cancer cells, allowing them to decide to "consume" according to the amount of "food". How many.

癌细胞竟被中国医生用这种方法弄死了

Hu Wei

The two "helpers" work synergistically to make cancer cells use glucose very conserved when the glucose content is low; to enter a "dormant" state without glucose; to resume growth immediately when there is glucose supply.

Therefore, if you want to effectively "starve" cancer cells, you must not only deprive glucose, but also destroy the synergistic effect of lactate anion and hydrogen ions. In the case of glucose starvation or deficiency, cancer cells die rapidly as long as either of these two factors is removed.

Using a base such as sodium bicarbonate (sodium bicarbonate) to remove hydrogen ions from the tumor destroys the synergy of lactate and hydrogen ions to quickly and efficiently kill tumor cells that are starved or deficient in glucose.

It is crucial to quickly convert basic research results into clinical treatment of cancer and benefit more patients.

Since 2012, the radiation interventional surgeons of the Second Affiliated Hospital of Zhejiang University School of Medicine, who has 30 years of clinical experience, have collaborated with the team to study the novel therapies for primary hepatocellular carcinoma, and named this method as "Arterial intubation chemoembolization for targeting lactate anion and hydrogen ions in tumors", referred to as "TILA-TACE".

癌细胞竟被中国医生用这种方法弄死了

Yan Ming

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