Chinese scientists successfully created African swine fever vaccine candidate vaccine May 28, 2019 Source: Chinese Journal of Science and Technology The reporter learned from the scientific research progress briefing held by the Chinese Academy of Agricultural Sciences on May 24 that the African swine fever vaccine independently developed by the Harbin Veterinary Research Institute of the hospital has achieved initial results: successful creation of vaccine candidates for African swine fever, laboratory research results It shows that it has good biosafety and immune protection effects. African swine fever is an acute, hemorrhagic and severe infectious disease caused by African swine fever virus infection of domestic pigs and various wild boars. It is called the “number one killer†of the pig industry. There are no vaccines and effective prevention and treatment drugs. In August 2018, China confirmed the first case of African swine fever. According to the person in charge of the research and development of the African swine fever vaccine of the Chinese Academy of Agricultural Sciences, after the outbreak, the Chinese Academy of Agricultural Sciences set up the African piglet prevention and control science and technology research project team for the first time. At present, the research team has made five progress in the African piglet vaccine creation stage: The first is to isolate the first African swine fever virus in China. The virus cell isolation and culture system and animal infection model were established, and the biological characteristics such as infectivity, pathogenicity and transmission ability were systematically studied, and the genomic characteristics and evolution of the African swine fever strain were revealed. Relationship; the second is to create a vaccine candidate for African swine fever; the third is that the two candidate vaccine strains have strong genetic stability in vitro and in vivo; the fourth is to clarify the minimum protective vaccination dose, to prove the safety of large dose and repeated dose vaccination; The trial product process research was initially completed. Up to now, the Chinese Academy of Agricultural Sciences African Hedgehog Prevention and Control Science and Technology Research Team has completed the genome-wide determination of African swine fever virus, cloned and expressed related genes, and constructed the immune mechanism, diagnostic test, and disinfection and pesticidal technology product research and development. Model animals and pigs have natural immune and inflammatory response signaling pathways, screen out multiple natural immunosuppressive viral genes, complete partial immunosuppressive mechanism research, and develop viruses with high detection speed, high sensitivity and specificity, and good stability. Rapid detection kit for nucleic acids and antigens; 12 species of cockroaches were collected, and effective prescriptions for rapid elimination of chemical drugs and plant-derived pesticides were screened; composite quaternary ammonium salt disinfectant formulations were screened and pilot tests were completed. Production research. The same day's report from the Chinese Academy of Agricultural Sciences also mentioned that, in the next step, the hospital will accelerate the pilot and clinical trials, as well as the research work on vaccine production, based on the research progress in the vaccine laboratory stage. X Ray High Collar Waistcoat Apron Dental Lead Apron,Patient Lead Apron,Dental Radiation Lead Apron With Collar,Lead Aprons With Thyroid Collars Longkou Kangxie Medical Instrument Co., Ltd , https://www.kangxiemedical.com