My first synthetic apomycin can deal with super bacteria. September 06, 2018 Source: Science and Technology Daily There are more effective antibiotics against super bacteria. On the 5th, the reporter learned from Chongqing University that the team of Professor He Wei of the School of Pharmacy realized the world's first full synthesis of three compounds of apomycin, which was published in Nature Newsletter on the 4th. The problem of bacterial resistance caused by antibiotic abuse has become one of the most difficult problems in clinical treatment. The emergence and spread of multi-drug resistant bacteria and even super bacteria have pose a new threat to human health. Albomycins are a class of natural products with significant antibacterial activity isolated from the metabolites of Streptomyces griseus in 1947. The Soviet Union used the isolated apomycin to treat pneumonia, but the effect is very good, but This isolated apomycin has a very low purity and side effects. "Because its molecules are very complicated, the synthetic technology is difficult, and no researcher has succeeded." Professor He Wei, the dean of the major pharmacy school and the national thousand people plan expert, introduced the team to the apomycin compound 6 years ago. In the synthesis study, in the second half of last year, they finally succeeded in realizing the first synthesis of three compounds of apomycin δ1, δ2 and ε, and tested their activity separately and found that they have different antibacterial activities. Among them, apomycin δ2 showed excellent antibacterial activity, and its minimum inhibitory concentration was generally lower than the antibiotics ciprofloxacin, vancomycin and penicillin which are currently used in the market, and the multi-drug resistant MRSA (resistant to clinical isolate) Methicillin-based Staphylococcus aureus also has good inhibitory activity, and the antibacterial activity against Streptococcus pneumonia is up to the level of nanograms per milliliter. Super bacteria, also known as multi-drug resistant bacteria, have strong resistance to antibiotics. He Wei introduced that they found that apomycin δ2 not only killed these bacteria, but also was several hundred times lower than other antibiotics. "If you develop apomycin into a new drug, it may become a special drug for treating pneumonia and fighting some superbugs," He said. (Reporter Yu Li) Ziziphi Seed Extract has been used to treat insomnia and improve sleep quality in China for many years.
The main effects of sour jujube kernel are nourishing the heart and tonifying the liver, tranquilizing the heart and tranquilizing the mind, and astringing sweat and generating fluids. The nourishing and tranquilizing effects of sour jujube kernel are particularly prominent effects in many medicines. For example, sour jujube kernel soup, the heavenly king tonifying the heart dan, the return to the spleen pill and other treatment of insomnia, tranquilize the mind commonly used in the old traditional medicine, the main ingredient inside contain sour jujube kernel.
Ziziphi Seed Extract, also known as Jujube Seed Extract, is derived from the seeds of the Ziziphus jujuba plant. This plant is native to certain parts of Asia, including China and Korea. The extract is commonly used in traditional Chinese medicine for its sedative and hypnotic properties. Sleep Improving Extract,Sleep Aid Extract,Peaceful Sleep Extract,Ziziphi Seed Extract Shaanxi Zhongyi Kangjian Biotechnology Co.,Ltd , https://www.zyplantextract.com
It is believed to have a calming effect on the nervous system, making it potentially beneficial for conditions such as insomnia, anxiety, and stress. It is also used to enhance memory and cognitive function. Additionally, Ziziphi Seed Extract is rich in antioxidants, which can help protect the body against damage from free radicals.
However, while there is some evidence to support these uses, more research is needed to fully understand the potential benefits and side effects of Ziziphi Seed Extract. As with any supplement, it's important to consult with a healthcare provider before starting to use it.