Science and Technology Daily, Beijing, May 7 (Reporter Zhang Mengran) The British "Nature News" magazine published a new medical advancement on the 7th: American scientists reported that they used the external organ support system to regenerate damaged lungs. Preliminary results show that the damaged pig lungs can be repaired and used for organ transplantation. Inhalation of stomach contents refers to the entry of substances into the respiratory tract. This common injury can cause the lungs to be used for transplantation. In view of the current shortage of transplant donors around the world, damaged lung regeneration technology is expected to expand the library of organs suitable for transplantation. This time, Matthew Bacheta, a researcher at Vanderbilt University in the United States, and colleagues studied the possibility of achieving transplant standards after severely damaged lung regeneration. The research team used pigs as the experimental object (the size and shape of the internal organs of pigs were similar to human organs and was also considered as a potential donor for organ transplantation), and the inhalation injury of gastric contents was reproduced in 8 pigs. The damaged lung is connected to the circulatory system of the recipient animal through an in vitro support system to maintain the organ. Studies have shown that with this cross-circulatory system, donor lungs can be maintained for up to 36 hours in pigs, allowing a range of therapeutic interventions to be performed. The system not only regenerates damaged lungs, but also enhances its function, and the regenerated lungs meet all transplant conditions. The researchers said that further research is needed to determine the functional lung capacity after lung transplantation and the safety of the method. Since human organ transplantation must be treated with immunosuppressive therapy, the impact of immunosuppression on lung recovery should be further evaluated in the future to alleviate the shortage of transplantable organs in the medical field. Source: Technology Daily ZHOUSHAN SINOMEGA BIOTECH ENGINEERING CO.,LTD , https://www.sinomegabiotech.com
:2019-05-08