Release date: 2015-08-04 Using multi-scale and multi-precision theoretical calculation strategies, Li Guohui, the national key laboratory of molecular dynamics dynamics of Dalian Institute of Chemical Physics, Chinese Academy of Sciences, teamed up with Yang Yongliang, a group of Dalian University of Technology, to discover the first drug in the world for the treatment of kidney cancer. Nie can be used to treat Alzheimer's disease. This discovery opens up new avenues for the development of new drugs and the “new use of old drugsâ€. Relevant research results have been published in the international chemical famous journal "Chemical Science". For hundreds of thousands of different kinds of proteins and biomolecules in human bodies, the objects that drug molecules can recognize and act are not unique. Therefore, a drug molecule that treats a disease may also interact with another bioprotein target to produce an unexpected therapeutic effect. At present, the development of new functions or new effects for existing drugs in the world has become a hot spot for drug research. According to Li Guohui, based on the trend of international new drug research, their research team uses computer combined with multi-scale and multi-precision theoretical calculation strategies to fully consider the three-dimensional physical and chemical properties similarity of biological targets and drug molecules themselves, as well as molecular dynamics simulation and Monte Carlo. Luo method, in close cooperation with several discipline laboratories such as Yang Yongliang's research group of Dalian University of Technology, from the drug database of the US Food and Drug Administration, the first discovery of the approved drug for the treatment of kidney cancer, pazopanib, can be used with the elderly. The drug target protein of dementia is tightly bound and further confirmed by long-term molecular dynamics simulation and large-scale Monte Carlo method. After the protein and drug binding ability test and the disease model animal pharmacology experiment, pazopanib can significantly alleviate the symptoms of the experimental mice, and the drug dosage is only 1/5 of the original. This discovery not only means that there will be a new way to treat Alzheimer's disease in the future, but patients can also greatly reduce the amount of drugs taken, thereby minimizing the side effects of drugs. Source: China Science and Technology Network - Technology Daily
Metatron Hunter 4025:
Description and Field of Application
The apparatus is intended to register psychophysics changes in system and allows to:
Metatron Hunter 4025,Metapathia Gr Hunter 4025,Metatron 4025 Nls,Metatron Gr Hunter 4025 Shenzhen Guangyang Zhongkang Technology Co., Ltd. , https://www.szlighttherapymachine.com
Purpose
The Metapathia-GR Hunter software can operate only with the telemetric nonlinear analysis data processing apparatus "Metatron" and its subsequent modifications. The telemetric nonlinear analysis data processing device is compatible with the IBM-type PCs and intended for studying reaction of a biological object to different types of the informational impact. "Metatron" allows correlating the measurement process with the process affecting it and performs the following.
Operations:
1) It measures J (0) which mirrors the change of the describing parameter, and the entropic potential relative to its ini- tial value;
2) It transforms continuous signal J (0) with the preset intervals of frequencies into a histogram (a row of numerical val-ues of scanned frequencies with serial numbers from 1.8 to 8.2 Hz.);
3) It sends the current W values to PC and displays the graph on the monitor simultaneously with its impact on the examinee.
4) It accumulates the W value in its memory unit, if observing the histogram is more convenient upon completion of the measurements;
5) It issues the scale-correlated commands required for regulating the effect on the examinee at testing;
6) It transmits the W values from the unit into PC memory upon completion of the measurements and saves them in unit memory of prior to the beginning of recording data of the next measurements.
Telemetric nonlinear analysis data processing apparatus "Metatron" (hereinafter "apparatus") can be used for non-linear analysis of biological structures and testing of biologically active supplements. The apparatus can also be used in research centers and scientific research facilities.
- Get qualitative estimation of functional condition in a form of topical analysis.
- Control effectiveness and results of different ways of treatment.
- Analyze dynamics of functional condition changes over period of time.
- Determine initial nidus of functional breach.
- Estimate character of changes using expert systems.
- Estimate basic characteristics of bio-system homeostasis.
