Oral cancer invasion site can be accurately labeled

December 13, 2018 Source: Health News Network

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A recent study by Professor Hu Qingang, dean of the Affiliated Stomatological Hospital of Nanjing University School of Medicine, found that tracking and localization of cancerous invasive sites by fluorescence can make the resection range more accurate and reliable. The research result of "Key Technology and Application of Oral Cancer Diagnosis and Treatment" has recently won the second prize of Jiangsu Science and Technology Award.

According to the researchers, in the field of stomatology, it has long been believed that the standard for complete resection of oral cancer is to determine whether there is residual tumor cells by local frozen biopsy during surgery. However, after years of research, the team found that this standard is not perfect, because local testing is too limited, and it does not prove that there is no cancer cell residue in the entire oral surgery area. The latest research results of the research group show that tracking and localization of cancer tissue invasion sites by fluorescence can make the resection range more accurate and reliable. Hu Qingang said that the study proved that the pathologically safe resection range must be more than 5 mm outside the front of the tumor to complete the removal of the diseased tissue. In addition, the team also found that atypical hyperplasia of oral mucosa is also an important factor affecting the recovery.

Relying on these clinical findings, the research team has improved the 5-year survival rate of oral cancer patients from 60% to 66% in the past 10 years, which has brought more survival opportunities to patients with oral cancer, and also provided clinical diagnosis and treatment for oral cancer. Scientific theory and experimental basis.

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