Abstract:
In order to prevent the influence of light, heat, oxygen and other drugs on the drug, and ensure that the drug is not affected by moisture and quality during the effective period, the plastic bottle of the tablet should have good sealing performance . Relevant national standards have clearly defined this, which is also an important indicator of each production enterprise.
Key words: tablet plastic bottle sealing performance test, sealing, tablet plastic bottle, seal tester
Body :
Tablet plastic bottles are widely used because of their light weight, high strength, not easy to break, good sealing performance, moisture resistance, hygiene, meet the special requirements of pharmaceutical packaging, and can be directly used for pharmaceutical packaging without cleaning or drying. Packaging of oral solid medicines and oral liquid medicines. In order to prevent the influence of light, heat, oxygen and other drugs on the drug, and ensure that the drug is not damp and does not deteriorate during the effective period, the plastic bottle of the tablet should have a good sealing property . Relevant national standards have clearly defined this, which is also an important indicator of each production enterprise. Next, Labthink combines the MFY-01 seal tester to provide a brief introduction to the sealing performance test of tablet plastic bottles.
Sealing performance refers to the reliability of a plastic bottle seal. This test ensures the integrity of the entire product package seal. In order to ensure that the drug is not damp and does not deteriorate during the validity period, the plastic bottle of the tablet should have a good sealing property. The relevant national standards have clearly defined this: take a certain number of tablet plastic bottles, and load each bottle. Appropriate amount of glass ball, tighten the cap (see below for torque).

Cover diameter ( mm )
Torque ( N · cm )
15~22
59~78
23~48
98~118
49~70
147~176

Then, place it in a container with a suction device, immerse it in water, and evacuate it to a vacuum of 27 kPa for 2 minutes. There must be no water or bubbles in the bottle. Labthink's MFY-01 seal tester uses vacuum principle to create a pressure difference between the sample and the sample immersed in water by vacuuming the vacuum chamber to observe the gas escape in the sample to determine the sealing performance of the sample. : By vacuuming the vacuum chamber, the sample is subjected to internal and external pressure difference, and the shape of the sample is recovered after the sample is expanded and the vacuum is released to determine the sealing performance of the sample. The experiment process only needs to input the corresponding pressure value and time, and the instrument can realize fully automatic test, convenient operation and friendly human-computer interaction. The above method is based on the principle of visual inspection. It is a qualitative test method. If you want to quantitatively test the sealing and leakage performance of the package, you can use the positive pressure method to seal the performance test equipment, such as Labthink LSSD-01 leakage and Seal strength tester.
Of course, after ensuring that the sealing index of the tablet plastic bottle is qualified, it is also necessary to control other indicators such as oxygen barrier and moisture resistance to ensure the quality of the product during the shelf life. For more information about related instruments, you can visit Languang for specific information. Jinan Languang Electromechanical Technology Co., Ltd. is willing to enhance exchanges and cooperation with enterprises and institutions in the industry.

Biochemical Incubator


Biochemical Incubator for environmental protection, health and epidemic prevention, drug testing, agricultural and livestock, aquatic and other scientific research, institutions and production sectors. Is the water analysis and BOD determination, bacteria, fungi, microbial culture, preservation, plant cultivation, breeding experiments dedicated thermostatic equipment. It is an important test facility for biology, genetic engineering, medicine, sanitation and epidemic prevention, environmental protection, agriculture, forestry, animal husbandry and other industries. Capacity: 150 liters, 250 liters Temperature range: 50 ℃ Temperature uniformity: ≤ ± 1 ℃ Temperature fluctuation: ≤ ± 1 ℃ Stainless steel liner, spray steel plate shell, polyurethane foam insulation With a large viewing angle observation window, microcomputer control lighting, digital display high precision. Unique stainless steel circulating air duct, forced air circulation, temperature uniformity.



Model Voltage Range of temperature
(°C)
Wave degree
of temperature
(°C)
Heating power Workroom size
(mm)
Capacity
SPX-70B 220V/
50HZ
0~65 ±1 300W 420*350*500 70L
SPX-150B 500W 500*400*750 150L
SPX-250B 800W 500*500*950 250L

Biochemical Incubator


Biochemical Incubator


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Biochemical Incubator

Biochemical Incubator

Biochemical Incubator




Biochemical Incubator,Laboratory Incubator,Microbiology Incubator,Culture Incubator

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